Estradiol is the most potent and prominent form of estrogen circulating in the female body. Estrogen is essential for the development and maintenance of the female reproductive system and secondary sex characteristics.
What is Estradiol?
Estradiol is a steroid hormone produced primarily by the ovaries. It plays a vital role in:
- Regulating the menstrual cycle
- Supporting pregnancy
- Maintaining bone and cardiovascular health
- Influencing brain function and behavior
During the menstrual cycle, estradiol levels fluctuate, stimulating growth of the uterine lining during the
proliferative phase. High estradiol triggers
ovulation and supports the uterine lining in the secretory phase. If pregnancy occurs, estradiol levels remain elevated to maintain the endometrium.
Estradiol works together with other hormones like progesterone to regulate the menstrual cycle. Abnormal estradiol levels can lead to conditions like
polycystic ovary syndrome (PCOS) or amenorrhea ( absence of periods).
Estradiol Production and Metabolism
Estradiol is produced by follicles in the ovaries when stimulated by other hormones like FSH and LH. Estradiol travels in the bloodstream bound to sex hormone-binding globulin (SHBG).
Estradiol exerts its effects by binding to estrogen receptors in various tissues like the uterus, breasts, bone, brain, liver, and heart. After completing its functions, estradiol is broken down by the liver and excreted.
If you suspect hormonal imbalances involving estradiol, consider getting tested at
Hormone Harmony Clinic. Our experts specialize in customized bioidentical hormone therapy to help regulate estrogen levels. Contact us today to take control of your hormonal health!